The American Society of Dermatopathology

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Interactive Case Study - January 2020

A progressively enlarging nodule on the face of a 32-year-old female

Rummit K. Dhillon, MS, IV; Narciss Mobini, MD

Question 1:

A 32-year-old Hispanic female presents with a 2.5cm well circumscribed, red-brown nodular growth on the left nasolabial fold. The lesion had been steadily increasing in size over the past year and is otherwise asymptomatic (Figure1). Biopsies of the lesion revealed the following histopathologic changes (Figures 2-5):
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Figure 1

Figure 2

Figure 3A

Figure 3B

Figure 4

Figure 5

Which of the following is the best diagnosis?