The American Society of Dermatopathology

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Interactive Case Study - September 2020

A 53-year-old male with multiple blisters on hands and forearms

Karah White, MD; Amy M. Kerkvliet, MD

Question 1:

A 53-year-old male with a history of alcohol abuse presented with multiple blisters and large erosions on his hands and forearms, which had been present for almost 2 years (Figure 1).  He works outside and denies excoriating the lesions.  A biopsy was performed (Figures 2-5).

Click this image to view the virtual slide.

Figure 1.

Figure 2.

Figure 3.

Figure 4.

Figure 5.

Which of the following is the best diagnosis?