Interactive Case Study - August 2021

Question 1:

A 47-year-old male presents to his dermatologist with a 1.1 x 1.0 cm flesh-colored papule on the left index finger near the nail bed. The lesion has been present for two years, has been gradually increasing in size, and does not cause pain. It is firm and solid to palpation. An excisional biopsy is performed.

Click the image below to view the virtual slide.


Figure 1.


Figure 2.


Figure 3. 


Figure 4. EMA


Figure 5a. CD34


Figure 5b. CD34


Figure 6. Pankeratin


Figure 7. S100


Figure 8. Rb1

 
Which of the following is the best diagnosis?
 

A.	Acquired digital fibrokeratoma

B.	Dermatofibrosarcoma protuberans

C.	Myxoid neurofibroma

D.	Sclerosing perineurioma

E.	Superficial acral fibromyxoma