Interactive Case Study - January 2022

‎60-year-old woman with a tender, rapidly growing nodule

Jaffar Khan, MBBS; Ahmed Khalid Alomari‎, MD

A 60-year-old woman presented with a tender, rapidly growing nodule in her chest. A deep punch biopsy was performed.

Click this image to view the virtual slide

Figure 1. Clinical image

Figure 2. H&E, low power

Figure 3. H&E, high power

Figure 4. CK20, high power

Figure 5. CK7, high power

Figure 6.TTF-1, high power

What is the best diagnosis?

A.	Basal cell carcinoma

B.	Cutaneous T-cell lymphoblastic lymphom

C.	Ewing sarcoma

D.	Metastatic small cell lung carcinoma

E.	Merkel cell carcinoma