The American Society of Dermatopathology

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Interactive Case Study - May 2022

66-year-old male with firm plaques on the trunk and extremities

Yujie Linda Liou, DO; Mara G. Beveridge, MD; Bethany Rohr, MD, FAAD

Question 1:

A 66-year-old male with a history of acute myeloid leukemia (AML), status post allogeneic hematogenous stem cell transplant, presented with firm, itchy, and painful skin lesions. The lesions were on the arms, legs, and abdomen and started about 2 years ago with rapid worsening on the legs in the past 3 months. Physical exam revealed ill-defined broad erythematous, brown to purple, reticulated firm plaques on the abdomen, flank, bilateral upper extremities, and lower legs. A biopsy from the abdomen was performed. 

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Which of the following is the best diagnosis?