The American Society of Dermatopathology

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Interactive Case Study - December 2013

Erythematous plaque on chest of 62-year-old female

Solomon Shockman, MD; Morgan Wilson, MD

Question 1:

A 62-year-old woman presented with an erythematous plaque on the mid left chest, which was neither pruritic nor painful (Figure 1).  

Figure 1. 


The plaque on the chest was biopsied. The histology is shown below (Figures 2-7).

Figure 2. H+E 20x


Figure 3. H+E 200x


Figure 4. H+E 600x


Figure 5. CD3 40x


Figure 6. CD20 40x


Figure 7. Cyclin D1 40x

What is the diagnosis?