The American Society of Dermatopathology

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Interactive Case Study - February 2015

Painless periorbital mass

Amanda F. Marsch, MD; Razan Massarani-Wafai, MD; Kelli Ann Hutchens, MD

Question 1:

A 50-year-old male presented with a slowly growing, painless periorbital mass of two-year duration. Excisional biopsy demonstrated the following histopathology (Figures 1-6).

Click this image to view the virtual slide for this case:

Figure 1. 1x

Figure 2. 5x

Figure 3. 3x

Figure 4. 8x

Figure 5. 6x

Figure 6. 18x

What is the best diagnosis?