The American Society of Dermatopathology

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Interactive Case Study - August 2015

Asymptomatic ecchymotic plaques on the chest

Emily M. Erstine, MD, MBA; Ivanka Kovalyshyn, DO

Question 1:

A 74-year-old man presented with a one-week history of an asymptomatic eruption of ecchymotic plaques on the chest with accompanying fever and lethargy.  A biopsy shows the following histopathology on H&E (Figures 1-4) and immunohistochemical staining (Figure 5).

Click on the image to view the virtual slide

Figure 1. H&E, 2x

Figure 2. H&E, 10x

Figure 3. H&E, 20x superficial

Figure 4. H&E, 20x deep

Figure 5. CD20, 10x

Which of the following is the best diagnosis?