Interactive Case Study - September 2017

Question 1:

A previously healthy 47-year-old male truck driver presents with an irritated, irregular, brownish-gray plaque on the sacrum and intergluteal cleft.  The H&E stain is shown below (Figure 1-3).   
 
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Figure 1

 
Figure 2

 
Figure 3

Which of the following is the best diagnosis?

A.	Lichen amyloidosis

B.	Lichen simplex chronicus

C.	Systemic amyloidosis

D.	Lichen planus

E.	Postinflammatory melanosis