The American Society of Dermatopathology

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Interactive Case Study - September 2017

47-year-old male with anosacral plaque

Ahmed K. Alomari, MD; Ian A. Gelarden, BS

Question 1:

A previously healthy 47-year-old male truck driver presents with an irritated, irregular, brownish-gray plaque on the sacrum and intergluteal cleft.  The H&E stain is shown below (Figure 1-3).   
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Figure 1

Figure 2

Figure 3

Which of the following is the best diagnosis?