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The American Society of Dermatopathology
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Case Study of the Month
View case study archive
Interactive Case Study - February 2018
Enlarging vulvar growth in a 51-year-old female
Amy L. Bischoff, BS; Soon Bahrami, MD
Question 1:
A 51-year-old female presented with an enlarging vulvar growth. Biopsy was performed and the histopathology is shown below (Figures 1-8).
Click the image to view the virtual slide
Figure 1: 20x
Figure 2: 100x
Figure 3: 200x
Figure 4: 400x
Figure 5: S-100, 200x
Figure 6: Desmin, 100x
Figure 7: HMB45, 100x
Figure 8: Smooth Muscle Actin, 100x
Which of the following is the best diagnosis?
A.
Primary cutaneous perivascular epithelioid cell tumor
B.
Balloon/clear cell melanoma
C.
Clear cell benign fibrous histiocytoma
D.
Distinctive dermal clear cell mesenchymal neoplasm
E.
Cutaneous metastasis of renal cell carcinoma